Senescence-Associated Beta-Galactosidase (SA-β-gal)

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2025-01-31 15-57-25The accumulation of Senescence-Associated Beta-Galactosidase (SA-β-gal)/Senescent Cells in multiple organs in mice following a Ketogenic Diet is reversed upon stopping the diet.
2025-01-31 15-53-41A Ketogenic Diet causes the accumulation of Senescence-Associated Beta-Galactosidase (SA-β-gal)/Senescent Cells in multiple organs in mice via an increase in p53 activity.
2025-01-31 15-26-35An intermittent Ketogenic Diet does not cause the accumulation of Senescence-Associated Beta-Galactosidase (SA-β-gal)/Senescent Cells in multiple organs in mice compared to a control diet or to a continuous ketogenic diet
2025-01-31 15-16-59A Ketogenic Diet can cause the accumulation of Senescence-Associated Beta-Galactosidase (SA-β-gal)/Senescent Cells in multiple organs in mice compared to a control diet independent of weight when Beta-Hydroxybutyrate (BHB) levels are maintained ~1.4-1.8 mM in the ketogenic group and ~0.8-1.0 mM in the control group. Ketogenic diet protein composition 10% of calories and control diet protein composition 10% of calories.
2025-01-31 14-40-42A Ketogenic Diet can cause the accumulation of Senescence-Associated Beta-Galactosidase (SA-β-gal)/Senescent Cells in multiple organs in mice compared to a control diet independent of weight when blood Beta-Hydroxybutyrate (BHB) levels are maintained ~1.4-2.0 mM in the ketogenic diet group and ~0.8-0.9 mM in the control group. Ketogenic diet protein composition 9.2% of calories vs. control diet protein composition 25% of calories.