Self-Renewal

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Takeaways1
2025-01-28 20-11-31Prolonged Fasting for at least 9 days may induce Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) symmetric Self-Renewal
Insights3
2025-01-30 14-40-02The reduction in circulating IGF1 availability during fasting is responsible for the fasting-induced symmetric Self-Renewal of mouse Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) after 72-hour Prolonged Fasting
2025-01-30 14-28-44The enhanced Self-Renewal program of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) from mice after 72-hour Prolonged Fasting is inherent to the LT-HSC cells and not related to the BM stromal niche cells
2025-01-29 11-24-44Prolonged Fasting for 72 hours induces symmetric Self-Renewal of mouse Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs)
Quick Notes1
2025-01-27 16-38-44Rapamycin restores the Self-Renewal capability of Hematopoietic Stem Cells (HSCs) in mice
Assumptions1
2025-01-28 21-21-27The increase in Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) asymmetric Self-Renewal seen after 72 hours of Prolonged Fasting in mouse bone marrow in chengProlongedFastingReduces2014 was not triggered earlier in the fasting time