Protein Kinase A Catalytic Subunit (PKACα)

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Insights3
2025-01-30 13-56-42Reducing expression of th Protein Kinase A Catalytic Subunit (PKACα) in mouse bone marrow causes proliferation of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs)
2025-01-29 10-57-27Ex vivo treatment of cells from mouse bone marrow with siRNA targeting the Protein Kinase A (PKA) catalytic subunit (Protein Kinase A Catalytic Subunit (PKACα)) increases the ratio of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) to total cells compared with untreated cells
2025-01-29 10-53-18Ex-vivo treatment of cells from mouse bone marrow with siRNA targeting the Protein Kinase A (PKA) catalytic subunit (Protein Kinase A Catalytic Subunit (PKACα)) does not affect the total number of cells compared to untreated cells
Assumptions1
2025-01-28 21-10-51The Protein Kinase A Catalytic Subunit (PKACα) siRNA used in chengProlongedFastingReduces2014 had no off-target effects