| 2025-01-30 14-56-06 | The total number of cycling Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) in mouse bone marrow increases by the end of 72-hour Prolonged Fasting |
| 2025-01-30 14-55-51 | The total number of cells in the bone marrow of mice is no different between mice at the end of 72-hour Prolonged Fasting vs. non-fasting mice. |
| 2025-01-30 14-54-39 | The total number of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) in mouse bone marrow increases by the end of 72-hour Prolonged Fasting |
| 2025-01-30 14-45-54 | The ratio of BrdU+ Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) to total bone marrow cells in mouse bone marrow is increased in mice after 72-hour Prolonged Fasting compared to non-fasting mice |
| 2025-01-30 14-44-30 | The ratio of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) to total CD45+ cells increases for LT-HSCs isolated from the BM of mice after 72-hour Prolonged Fasting compared to those of non-fasted mice upon 3-day co-culture with Lin-CD45- stromal cells from the bone marrow of 72-hour-fasted mice |
| 2025-01-30 14-43-30 | The ratio of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) to total CD45+ cells increases for LT-HSCs isolated from the bone marrow of mice after 72-hour Prolonged Fasting mice compared to those of non-fasted mice upon 3-day co-culture with Lin-CD45- stromal cells from the bone marrow of non-fasted mice |
| 2025-01-30 14-41-07 | The ratio of total Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) to total bone marrow cells in mouse bone marrow is increased in mice after 72-hour Prolonged Fasting compared to non-fasting mice |
| 2025-01-30 14-40-02 | The reduction in circulating IGF1 availability during fasting is responsible for the fasting-induced symmetric Self-Renewal of mouse Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) after 72-hour Prolonged Fasting |
| 2025-01-30 14-28-44 | The enhanced Self-Renewal program of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) from mice after 72-hour Prolonged Fasting is inherent to the LT-HSC cells and not related to the BM stromal niche cells |
| 2025-01-30 14-22-58 | The % of mouse Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) in S-G2-M is increased at the end of 72-hour Prolonged Fasting compared with non-fasting mice |
| 2025-01-30 14-21-44 | The % of mouse Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) in G1 Phase is increased at the end of 72-hour Prolonged Fasting compared with non-fasting mice |
| 2025-01-30 14-20-22 | The % of mouse Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) in G0 Phase is reduced at the end of 72-hour Prolonged Fasting compared with non-fasting mice |
| 2025-01-30 14-07-34 | Refeeding with ~0.4 g/kg protein after 5-day Prolonged Fasting allows serum IGF1 levels to continue decreasing when refeeding with 552-799 kcal/day (10.8 kcal/kg) but not 1797-2579 kcal/day (35.1 kcal/kg) |
| 2025-01-30 13-51-11 | Plasma levels of IGFBP1 are increased by 11.4-fold after 72-hour Prolonged Fasting compared with non-fasted mice |
| 2025-01-30 13-51-06 | Plasma levels of IGFBP3 are decreased by 42% in mice after 72-hour Prolonged Fasting compared with non-fasting mice |
| 2025-01-30 12-28-26 | Plasma levels of IGF1 are reduced by 70% in mice after 72-hour Prolonged Fasting compared with non-fasting mice |
| 2025-01-30 12-22-21 | Mice have a blood Beta-Hydroxybutyrate (BHB) level of ~2.25 mM after 48 hours of Prolonged Fasting |
| 2025-01-29 11-25-02 | Prolonged Fasting for 9 days after 3 days of Calorie Restriction reduces serum IGF1 by at least 71% |
| 2025-01-30 12-10-44 | It takes 48-72 hours of Prolonged Fasting for Protein Kinase A (PKA) activity to decrease in the bone marrow cells of mice |
| 2025-01-30 12-05-44 | Injecting IGF1 into fasting mice prevented an increase in the ratio of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) to total bone marrow cells at 72 hours of Prolonged Fasting compared with 72-hour-fasted mice that were not injected with IGF1 while fasting |
| 2025-01-30 11-55-39 | Injecting IGF1 into fasting mice prevented an increase in the number of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) at 72 hours of Prolonged Fasting compared with 72-hour-fasted mice that were not injected with IGF1 while fasting |
| 2025-01-29 11-26-23 | Prolonged Fasting for 9 days reduces circulating IGF1 by 71% |
| 2025-01-29 11-24-44 | Prolonged Fasting for 72 hours induces symmetric Self-Renewal of mouse Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) |
| 2025-01-29 11-24-22 | Prolonged Fasting for 72 hours reduces circulating IGF1 levels by 70-75% in mice |
| 2025-01-29 11-23-24 | Prolonged Fasting for 7 days reduces circulating IGF1 by 62% |
| 2025-01-29 11-06-02 | Prolonged Fasting for 3 days reduces circulating IGF1 levels by 41-54% |
| 2025-01-29 11-05-25 | Prolonged Fasting for 7 days after 3 days of Calorie Restriction reduces serum IGF1 by at least 62% |
| 2025-01-29 11-04-37 | Prolonged Fasting for 5 days reduces serum IGF1 by 64% |
| 2025-01-29 11-04-24 | Prolonged Fasting for 5 days reduces circulating IGF1 levels by 53-64% |
| 2025-01-29 11-03-54 | Prolonged Fasting for 5 days after 3 days of Calorie Restriction reduces serum IGF1 by at least 53% |
| 2025-01-29 11-02-49 | Prolonged Fasting for 4 days reduces serum IGF1 levels by 59% |
| 2025-01-29 11-02-36 | Prolonged Fasting for 4 days reduces circulating IGF1 levels by 59% |
| 2025-01-29 11-01-45 | Prolonged Fasting for 3 days reduces serum IGF1 by 54% |
| 2025-01-29 11-01-02 | Prolonged Fasting for 3 days reduces serum IGF1 by 42% |
| 2025-01-29 11-00-47 | Prolonged Fasting for 3 days after 3 days of Calorie Restriction reduces serum IGF1 by at least 41% |
| 2025-01-29 10-57-40 | Prolonged Fasting for 10 days after 3 days of Calorie Restriction reduces serum IGF1 by at least 75% |
| 2025-01-29 10-52-38 | Prolonged Fasting for 10 days reduces circulating IGF1 by 75% |
| 2025-01-29 10-47-07 | Circulating IGF1 is reduced by ~75% at the end of 72-hour Prolonged Fasting compared with non-fasting mice |
| 2025-01-29 10-35-55 | 9 days of water-only Prolonged Fasting in humans is equivalent to a 3-day water-only fast in mice in terms of its effects on IGF1 availability |
| 2025-01-29 10-27-59 | 3 days of water-only Prolonged Fasting is at least equivalent to a 4-day mouse Fasting-Mimicking Diet (FMD) in terms of its effects on IGF1 availability |
| 2025-01-29 10-23-03 | 72 hours of Prolonged Fasting around Chemotherapy is better at keeping blood Lymphocyte counts from reducing than fasting for 24 hours around chemotherapy for platinum-based doublet chemotherapy |
| 2025-01-29 10-17-26 | 48 hours of Prolonged Fasting reduces serum IGF1 by ~66% in 6-month-old mice |
| 2025-01-29 10-17-22 | 48 hours of Prolonged Fasting does not reduce serum IGF1 in 24-month-old mice |
| 2025-01-20 19-12-04 | Muscle Stem Cells (MuSCs, Satellite Stem Cells) have reduced RNA content in mice at the end of 2.5-day Prolonged Fasting compared to non-fasted mice as assessed by Pyronin Y |
| 2025-01-20 19-29-10 | Fewer Muscle Stem Cells (MuSCs, Satellite Stem Cells) from mice undergoing 2.5-day Prolonged Fasting are in S Phase at 72 hours after muscle injury compared to non-fasted mice as assessed by EdU incorporation |
| 2025-01-20 19-21-47 | Fewer Muscle Stem Cells (MuSCs, Satellite Stem Cells) enter S Phase when cultured ex vivo when the stem cells are isolated from mice after 2.5-day Prolonged Fasting mice compared to non-fasted mice as assessed by EdU incorporation |
| 2025-01-20 19-17-51 | Muscle Stem Cells (MuSCs, Satellite Stem Cells) exhibit reduced basal oxygen consumption at the end of 2.5-day Prolonged Fasting in mice compared with non-fasted mice |
| 2025-01-20 18-42-42 | Muscle Stem Cells (MuSCs, Satellite Stem Cells) have ~40% reduced content of Mitochondria (number and/or size) in mice at the end of 2.5-day Prolonged Fasting compared to non-fasted mice as assessed by MitoTracker |
| 2025-01-20 18-28-57 | Muscle Stem Cells (MuSCs, Satellite Stem Cells) enter a state of Deep Quiescence at the end of 2.5-day Prolonged Fasting in mice |
| 2025-01-20 15-44-11 | Mice have a blood Beta-Hydroxybutyrate (BHB) level of ~2.75 mM after 60 hours of Prolonged Fasting |