| 2025-01-28 19-54-04 | ~50% of patients with Hypophosphatasia have a ALPL gene variant |
| 2025-01-28 19-47-00 | The urine Phosphoethanolamine (PEA)/Creatinine ratio is elevated in Hypophosphatasia patients |
| 2025-01-28 19-42-55 | Reduced plasma Alkaline Phosphatase (ALP) and elevated plasma Pyridoxal 5'-Phosphate (PLP, Vitamin B6), Pyrophosphate (PPi), and/or Phosphoethanolamine (PEA) can help diagnose Hypophosphatasia |
| 2025-01-28 19-42-00 | Serum Osteocalcin may be near the low end of normal in patients with Hypophosphatasia |
| 2025-01-28 19-26-35 | Lumbar Spine T scores for Bone Mineral Density (BMD) may be normal or higher than normal in patients with Hypophosphatasia |
| 2025-01-28 19-22-50 | Osteocalcin may be a useful biomarker to track in patients with Hypophosphatasia |
| 2025-01-28 19-22-04 | Most people diagnosed with Hypophosphatasia suspect that they had symptoms during childhood |
| 2025-01-28 19-22-01 | Most people with Hypophosphatasia are diagnosed before age 18 |
| 2025-01-28 19-18-53 | Hypophosphatasia can cause Hyperphosphatemia and Hypercalcuria |
| 2025-01-28 19-14-02 | It is possible to have normal serum Alkaline Phosphatase (ALP) levels periodically with Hypophosphatasia |
| 2025-01-28 19-07-37 | Elevated serum Pyridoxal 5'-Phosphate (PLP, Vitamin B6) can help diagnose Hypophosphatasia |
| 2025-01-28 19-04-40 | High doses of Vitamin D and/or Calcium (Ca) can make the symptoms and complications of Hypophosphatasia worse |
| 2025-01-28 18-58-50 | Adult presentation of Hypophosphatasia includes a wide variety of symptoms such as metatarsal stress fractures, chronic muscle pain, reduced muscle strength, and bone pain |
| 2025-01-22 12-28-31 | Increased Bone Mineral Density (BMD) in the lumbar spine of patients with Hypophosphatasia is associated with increased risk of fracture |
| 2025-01-22 13-09-07 | Hypophosphatasia patients with ALPL variants can be identified based on Alkaline Phosphatase (ALP) < 25 IU/L and Pyridoxal 5'-Phosphate (PLP, Vitamin B6) > 180 nmol/L |
| 2025-01-22 13-04-08 | Vitamin D deficiency may not elevate Alkaline Phosphatase (ALP) levels in patients with Hypophosphatasia |
| 2025-01-22 12-40-53 | Serum Alkaline Phosphatase (ALP) can be elevated by Hyperparathyroidism in patients with Hypophosphatasia |
| 2025-01-22 12-36-35 | Correcting a Vitamin D deficiency does not alter serum Alkaline Phosphatase (ALP) levels in patients with Hypophosphatasia |
| 2025-01-22 12-33-11 | Bone Mineral Density (BMD) of the femoral neck is not associated with Alkaline Phosphatase (ALP) levels in patients with Hypophosphatasia |
| 2025-01-22 12-26-56 | Increased levels of Pyridoxal 5'-Phosphate (PLP, Vitamin B6) and Phosphoethanolamine (PEA) are associated with increased Bone Mineral Density (BMD) in the lumbar spine of patients with Hypophosphatasia |
| 2025-01-22 12-25-51 | Lower levels of serum Alkaline Phosphatase (ALP) are associated with increased Bone Mineral Density (BMD) in the Lumbar Spine in patients with Hypophosphatasia |
| 2025-01-22 12-18-55 | Vitamin A does not increase serum Alkaline Phosphatase (ALP) levels in patients with Hypophosphatasia |