| 2025-01-29 11-46-14 | Muscle Stem Cells (MuSCs, Satellite Stem Cells) are reduced in size by ~10% in mice by the end of 1 week of 3x/day intraperitoneal 200 mg/kg racemic Racemic Beta-Hydroxybutyrate (DL-BHB) and 200 mg/kg Acetoacetate (AcAc) injections compared to control mice |
| 2025-01-20 20-41-50 | Fewer Muscle Stem Cells (MuSCs, Satellite Stem Cells) from mice treated with intraperitoneal injections of 200 mg/kg/day Beta-Hydroxybutyrate (BHB) + 200 mg/kg/day Acetoacetate (AcAc) are in S Phase compared to control mice as assessed by Edu incorporation |
| 2025-01-20 20-37-16 | Fewer Muscle Stem Cells (MuSCs, Satellite Stem Cells) enter S Phase when cultured ex vivo when the stem cells are isolated from mice treated with 3x/day intraperitoneal injections of 200 mg/kg Beta-Hydroxybutyrate (BHB) + 200 mg/kg Acetoacetate (AcAc) compared to control mice as assessed by EdU incorporation |
| 2025-01-20 20-32-54 | Muscle Stem Cells (MuSCs, Satellite Stem Cells) exhibit reduced basal oxygen consumption at the end of 7 days of 3x/day intraperitoneal 200 mg/kg Beta-Hydroxybutyrate (BHB) + 200 mg/kg Acetoacetate (AcAc) injections in mice compared with control mice |
| 2025-01-20 20-19-43 | Muscle Stem Cells (MuSCs, Satellite Stem Cells) have reduced content of Mitochondria (number and/or size) in mice at the end of 7 days of 3x/day intraperitoneal 200 mg/kg Beta-Hydroxybutyrate (BHB) + 200 mg/kg Acetoacetate (AcAc) injections compared to control mice as assessed by MitoTracker and MitoSox |
| 2025-01-20 20-12-30 | Muscle Stem Cells (MuSCs, Satellite Stem Cells) enter a state of Deep Quiescence at the end of 1 week of 3x/day intraperitoneal injections of 200 mg/kg Beta-Hydroxybutyrate (BHB) + 200 mg/kg Acetoacetate (AcAc) in mice |