2025-01-30 15-34-20

Content

Urolithin A slows the progression of Pfirrmann Grade at a dose of 25 mg/kg/day when taken for 4 weeks after an Intervertebral Disc (IVD) puncture at 12 weeks of age compared to rats not fed urolithin A

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liuUrolithinInhibitsCatabolic2018 - Materials and methods (surgical procedure)
liuUrolithinInhibitsCatabolic2018 - Materials and methods (radiographic study of the disc height and magnetic resonance imaging (MRI))
liuUrolithinInhibitsCatabolic2018 - Materials and methods (animals)
liuUrolithinInhibitsCatabolic2018 - Figure 5B
liuUrolithinInhibitsCatabolic2018 - Figure 5A

Original Sources1	Citations
liuUrolithinInhibitsCatabolic2018	Liu, Huiyong, Honglei Kang, Chao Song, Zuowei Lei, Li Li, Jianfeng Guo, Yong Xu, Hanfeng Guan, Zhong Fang, and Feng Li. “Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration in Vivo.” Frontiers in Pharmacology 9 (2018): 1043. https://doi.org/10.3389/fphar.2018.01043.