2025-01-30 15-28-05

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Urolithin A reduces the number of TUNEL-positive cells in the Nucleus Pulposus at a dose of 25 mg/kg/day when taken for 4 weeks after an Intervertebral Disc (IVD) puncture at 8 weeks of age compared to rats not fed urolithin A

Source Content5
linUrolithinAinducedMitophagy2020 - Materials and methods (experimental design)
linUrolithinAinducedMitophagy2020 - Materials and methods (animal model)
linUrolithinAinducedMitophagy2020 - Materials and methods (TUNEL staining)
linUrolithinAinducedMitophagy2020 - Figure 6F
linUrolithinAinducedMitophagy2020 - Figure 6E

Original Sources1	Citations
linUrolithinAinducedMitophagy2020	Lin, Jialiang, Jinru Zhuge, Xuanqi Zheng, Yuhao Wu, Zengjie Zhang, Tianzhen Xu, Zaher Meftah, et al. “Urolithin A-Induced Mitophagy Suppresses Apoptosis and Attenuates Intervertebral Disc Degeneration via the AMPK Signaling Pathway.” Free Radical Biology & Medicine 150 (April 2020): 109–19. https://doi.org/10.1016/j.freeradbiomed.2020.02.024.