2025-01-30 15-26-59

Content

Urolithin A reduces the knee OARSI score of mice at a dose of 250 mg/kg/day, but not 50 mg/kg/day, compared to control when taken for 8 weeks after the induction of experimental Osteoarthritis at 4 months of age

Source Content3
damicoUrolithinImprovesMitochondrial2022 - Figure 3B
damicoUrolithinImprovesMitochondrial2022 - Experimental procedures (mice)
damicoUrolithinImprovesMitochondrial2022 - Experimental procedures (histological analysis of knee joints cartilage degeneration (OARSI score))

Original Sources1	Citations
damicoUrolithinImprovesMitochondrial2022	D’Amico, Davide, Merissa Olmer, Andréane M. Fouassier, Pamela Valdés, Pénélope A. Andreux, Chris Rinsch, and Martin Lotz. “Urolithin A Improves Mitochondrial Health, Reduces Cartilage Degeneration, and Alleviates Pain in Osteoarthritis.” Aging Cell 21, no. 8 (August 2022): e13662. https://doi.org/10.1111/acel.13662.