2025-01-30 14-29-17

Content

The ideal single dose for injecting Hypoxic-Cultured Autologous Mesenchymal Stem Cells (MSCs) into the Annulus Fibrosus of a torn L5-S1 Intervertebral Disc (IVD) to improve overall quality of life after 4+ years may be 35.9 million cells

References

Source Content7
elabdIntradiscalInjectionAutologous2016 - table 3
elabdIntradiscalInjectionAutologous2016 - table 1
elabdIntradiscalInjectionAutologous2016 - results (patient 5)
elabdIntradiscalInjectionAutologous2016 - results (patient 4)
elabdIntradiscalInjectionAutologous2016 - results (patient 3)
elabdIntradiscalInjectionAutologous2016 - results (patient 2)
elabdIntradiscalInjectionAutologous2016 - results (patient 1)

Original Sources1	Citations
elabdIntradiscalInjectionAutologous2016	Elabd, Christian, Christopher J. Centeno, John R. Schultz, Gregory Lutz, Thomas Ichim, and Francisco J. Silva. “Intra-Discal Injection of Autologous, Hypoxic Cultured Bone Marrow-Derived Mesenchymal Stem Cells in Five Patients with Chronic Lower Back Pain: A Long-Term Safety and Feasibility Study.” Journal of Translational Medicine 14, no. 1 (September 1, 2016): 253. https://doi.org/10.1186/s12967-016-1015-5.

Original Sources1

Citations

elabdIntradiscalInjectionAutologous2016

Elabd, Christian, Christopher J. Centeno, John R. Schultz, Gregory Lutz, Thomas Ichim, and Francisco J. Silva. “Intra-Discal Injection of Autologous, Hypoxic Cultured Bone Marrow-Derived Mesenchymal Stem Cells in Five Patients with Chronic Lower Back Pain: A Long-Term Safety and Feasibility Study.” Journal of Translational Medicine 14, no. 1 (September 1, 2016): 253. https://doi.org/10.1186/s12967-016-1015-5.