2025-01-30 14-28-44
Content
- The enhanced Self-Renewal program of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) from mice after 72-hour Prolonged Fasting is inherent to the LT-HSC cells and not related to the BM stromal niche cells
References
| Insights2 | |
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| 2025-01-30 14-44-30 | The ratio of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) to total CD45+ cells increases for LT-HSCs isolated from the BM of mice after 72-hour Prolonged Fasting compared to those of non-fasted mice upon 3-day co-culture with Lin-CD45- stromal cells from the bone marrow of 72-hour-fasted mice |
| 2025-01-30 14-43-30 | The ratio of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) to total CD45+ cells increases for LT-HSCs isolated from the bone marrow of mice after 72-hour Prolonged Fasting mice compared to those of non-fasted mice upon 3-day co-culture with Lin-CD45- stromal cells from the bone marrow of non-fasted mice |
| Original Sources1 | Citations |
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| chengProlongedFastingReduces2014 | Cheng, C.-W., Adams, G.B., Perin, L., Wei, M., Zhou, X., Lam, B.S., Da Sacco, S., Mirisola, M., Quinn, D.I., Dorff, T.B., Kopchick, J.J., Longo, V.D., 2014. Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. Cell Stem Cell 14, 810–823. https://doi.org/10.1016/j.stem.2014.04.014 |