2025-01-30 14-05-50
Content
- Refeeding causes Apoptosis in Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) Senescent Cells following two consecutive Fasting-Mimicking Diet (FMD) cycles
References
| Assumptions3 | |
|---|---|
| 2025-01-29 09-50-38 | cas3 is a marker of apoptosis in human cells |
| 2025-01-29 09-46-09 | p16 is a marker of senescence in humans |
| 2025-01-28 21-19-18 | The effect of Fasting-Mimicking Diet (FMD) cycles on Senescent Cells does not depend on age |
| Insights4 | |
|---|---|
| 2025-01-30 14-26-56 | The % of cas3+p16+ Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) increases from ~1% to ~3% in the bone marrow of 22-month-old mice at 24 hours after Refeeding following two consecutive Fasting-Mimicking Diet (FMD) cycles |
| 2025-01-30 14-25-13 | The % of cas3+p16+ Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) in 22-month-old mice is not affected by a Fasting-Mimicking Diet (FMD) cycle |
| 2025-01-30 14-24-58 | The % of cas3+ Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) increases from ~1% to ~3% in the bone marrow of 22-month-old mice at 24 hours after Refeeding following two consecutive Fasting-Mimicking Diet (FMD) cycles |
| 2025-01-30 14-23-59 | The % of cas3+ Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) in 22-month-old mice is not affected by a Fasting-Mimicking Diet (FMD) cycle |
| Original Sources1 | Citations |
|---|---|
| longoUtilizationFastingMimickingDiet2023 | Longo, V.D., Brandhorst, S., Guidi, N., Crupi, A.N., 2023. Utilization of a Fasting-Mimicking Diet to Reduce Senescent Cells and Inflammation. 20230037534. |