2025-01-30 11-55-39
Content
- Injecting IGF1 into fasting mice prevented an increase in the number of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) at 72 hours of Prolonged Fasting compared with 72-hour-fasted mice that were not injected with IGF1 while fasting
References
| Insights2 | |
|---|---|
| 2025-01-30 14-55-51 | The total number of cells in the bone marrow of mice is no different between mice at the end of 72-hour Prolonged Fasting vs. non-fasting mice. |
| 2025-01-30 12-05-44 | Injecting IGF1 into fasting mice prevented an increase in the ratio of Bone Marrow Long-Term Hematopoietic Stem Cells (BM LT-HSCs) to total bone marrow cells at 72 hours of Prolonged Fasting compared with 72-hour-fasted mice that were not injected with IGF1 while fasting |
| Original Sources1 | Citations |
|---|---|
| chengProlongedFastingReduces2014 | Cheng, C.-W., Adams, G.B., Perin, L., Wei, M., Zhou, X., Lam, B.S., Da Sacco, S., Mirisola, M., Quinn, D.I., Dorff, T.B., Kopchick, J.J., Longo, V.D., 2014. Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. Cell Stem Cell 14, 810–823. https://doi.org/10.1016/j.stem.2014.04.014 |