2025-01-29 10-41-13
Content
- A Urolithin A dose of 25 mg/kg/day in a rat equates to 4 mg/kg/day in a human
References
| Insights1 | |
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| 2025-01-29 10-38-49 | A rat dose in mg/kg can be divided by 6.2 to approximate an equivalent human dose in mg/kg |
| Original Sources1 | Citations |
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| usfdaEstimatingMaximumSafe2018 | USFDA. “Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers.” FDA, December 1, 2018. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/estimating-maximum-safe-starting-dose-initial-clinical-trials-therapeutics-adult-healthy-volunteers. |