2025-01-29 10-39-17
Content
- A Urolithin A dose of 2.5 mg/kg/day in a mouse is equivalent to 0.2 mg/kg/day in a human
References
| Insights1 | |
|---|---|
| 2025-01-29 10-35-05 | A mouse dose in mg/kg can be divided by 12.3 to approximate an equivalent human dose in mg/kg |
| Original Sources1 | Citations |
|---|---|
| usfdaEstimatingMaximumSafe2018 | USFDA. “Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers.” FDA, December 1, 2018. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/estimating-maximum-safe-starting-dose-initial-clinical-trials-therapeutics-adult-healthy-volunteers. |